Autism Spectrum Disorder. Autistic disorder
Conditions
Interventions
Intervention 1: Intervention group: Patients with autism disorder will be treated with combination of risperidone with ondansetron for 8 weeks. Over 40kg and in case of ondansetron is 05 mg / kg / day
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to 17 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:1-Having criteria for diagnosing autism spectrum disorder based on DSM-5 clinical interview and semi-structured K-SADS interview -. 6 -15years old -To participate in the study with the written consent of the patient's guardian and with the patient's consent
Exclusion criteria
Exclusion criteria: Any active physical illness There is a psychiatric diagnosis other than mental retardation - taking any medication affecting mental status other than risperidone at least two weeks prior to the study, A history of ondansetron allergy Liver or heart disease or neurological or associated kidney disease Causing any drug side effects The patient's or guardian's unwillingness to continue to be involved in the research project for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of Autism Spectrum Disorder. Timepoint: Baseline and weeks 4and 8. Method of measurement: Childhood Autism Rating Scale (CARS).;Relationship and Behavior. Timepoint: Baseline and weeks 4and 8. Method of measurement: Aberrant Behavior Checklist-Community (ABC-C).;Self-concept. Timepoint: Baseline and weeks 4and 8. Method of measurement: Self- Conception Questionnaire.;Psychiatric diagnosis of autism disorder. Timepoint: Baseline and weeks 4and 8. Method of measurement: kiddie-sads-present and lifetime version (k-sads-pl). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRshim Badrfam
Tehran University of Medical Sciences
Outcome results
None listed