BIPOLAR DISORDER. Bipolar mood disorder
Conditions
Interventions
Intervention 1: Fifty Patients with type 1 bipolar disorder in the mania phase are randomly divided into two groups. 25patients in the intervention group receive standard lithium carbonate and vitamin
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Subjects aged 18 to 65 years old Diagnosis of type 1 bipolar disorder in early-onset mania based on DSM-V diagnostic criteria (by semi-structured interview by a psychiatrist and confirmation of diagnosis with a score of at least 20 on the Young Mania Scale). Consent of the possibility of being present on the patient's legal guardian
Exclusion criteria
Exclusion criteria: Absence of psychosis in patients A history of drug sensitivity to lithium carbonate or vitamin B6 Absence of diagnoses of schizophrenia, delirium, anorexia neurosis, bulimia neurosis, autism, substance abuse (at least 3 months ago), retardation Bipolar type 2 seizures (Existence of suicide due to lack of suicide risk factor for use of evaluated drugs as well as weekly weekly medications and low weekly prescription drugs are not included in the plan).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mania Symptoms by Young Mania Questionnaire. Timepoint: Baseline and weeks 3, 4, and 8 after vitamin B6 start. Method of measurement: Yang Mania questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality. Timepoint: Baseline and weeks 3, 4, and 8 after vitamin B6 start. Method of measurement: Petersburg questionnaire.;Nutrition and appetite status. Timepoint: Baseline and weeks 3, 4, and 8 after vitamin B6 start. Method of measurement: Appetite Rating Scale.;Mini mental status. Timepoint: Baseline and weeks 3, 4, and 8 after vitamin B6 start. Method of measurement: Mini mental status examination.;Brain Mapping. Timepoint: Baseline and week , 8 after vitamin B6 start. Method of measurement: QEEG | Quantitative Electroencephalogram Test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactRahim Badrfam
Tehran University of Medical Sciences
Outcome results
None listed