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Edaravone in COVID-19

Effect of edaravone on clinical improvement and outcome of patients with respiratory distress syndrome caused by COVID-19

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200317046797N6
Enrollment
30
Registered
2020-06-18
Start date
2020-06-21
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with COVID-2019. Coronavirus infection, unspecified

Interventions

Intervention 1: Intervention group: 15 patients with COVID-19 in addition to a standard regimen will receive 30 mg intravenous infusion edaravone (C10H10N2O, Zist Daroo Co., Iran) every 12 hours for 1

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with COVID-19-induced pneumonia confirmed with Polymerase chain reaction (PCR) Patients with COVID-19-induced pneumonia confirmed with chest CT scan results 18 to 80 years old Patients with acute respiratory distress syndrome (ARDS) according to Berlin ARDS criteria

Exclusion criteria

Exclusion criteria: Patients who are participating in other drug clinical trials Pregnant or lactating women Patient with drug allergy Patients on mechanical ventilation Patients with expected survival duration< 24 h

Design outcomes

Primary

MeasureTime frame
Hospitalization days. Timepoint: At baseline and discharge time. Method of measurement: Counting the days.;Need for mechanical ventilation. Timepoint: From baseline to discharge time. Method of measurement: Observation and documents.;Condition of discharge (death or recovery). Timepoint: End of hospitalization. Method of measurement: Observation and documents.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Varshochi

Tabriz University of Medical Sciences

varshochim@tbzmed.ac.ir+98 41 3335 2898

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026