Skip to content

The effect of platelet rich plasma in lateral ankle sprain

The effect of platelet rich plasma (PRP) on pain and function in patients with lateral ankle sprain after modified Brostrom surgery, a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200307046714N1
Enrollment
20
Registered
2022-01-15
Start date
2022-01-20
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lateral ankle sprain. Sprain of unspecified ligament of ankle

Interventions

Intervention 1: Intervention group: In this group of patients, 50 ccs of peripheral blood will be taken from each patient by a 50cc syringe in the first, second, and sixth weeks after surgery, then ce

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Grade 3 (severe) ligament injury based on clinical and imaging criteria and no ankle fracture

Exclusion criteria

Exclusion criteria: Pregnancy Breastfeeding Those who intend to become pregnant History of peripheral vascular diseases Rheumatoid Arthritis Knee or ankle osteoarthritis Ankylosing spondylitis Foot deformities Diabetes Neurological disorders Psychiatric disorders History of surgery and active infection at the site of injury

Design outcomes

Primary

MeasureTime frame
Determination of ankle pain. Timepoint: The first visit, three months after surgery, six months after surgery. Method of measurement: Questionnaire (VAS).;Determination of ankle function. Timepoint: The first visit, three months after surgery, six months after surgery. Method of measurement: Questionnaire (AOFAS).;Determine the ankle total range of motion (total ROM). Timepoint: The first visit, three months after surgery, six months after surgery. Method of measurement: Manual joiniometry.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHooshmand Zarei, MD

Shahid Beheshti University of Medical Sciences

hooshmand.z1994@gmail.com+98 21 4409 8132

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026