Effect of Gabapentin on prevention of Delirium

The effect of Gabapentin on prevention of delirium in patients undergoing coronary artery bypass graft surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200306046706N1

Enrollment

Registered

2020-04-16

Start date

2018-09-23

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Heart Disease, Delirium, Open Coronary Heart Surgery. Delirium due to known physiological condition

Interventions

Intervention 1: Intervention group: Gabapentin 400 mg capsule, daily, for three days, with sufficient water in the morning, prepared by the Pharmacology Group. Intervention 2: Control group: Multivita

Eligibility

Sex/Gender

All

Age

45 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients undergoing Coronary Artery Bypass Graft Surgery

Exclusion criteria

Exclusion criteria: History of taking anticonvulsants, History of Gabapentin drugs consumption in the last two weeks History of proven psychological problems Emergency surgery ICU Admision before surgeon Delirium before surgery History of previous cardiac surgery

Design outcomes

Primary

Measure	Time frame
Permitted delirium according to the CAM-IC criteria. Timepoint: Examine delirium twice daily, days 1, 2, 3. Method of measurement: Confusion Assessment Method-ICU.	—

Secondary

Measure	Time frame
Postoperative mortality. Timepoint: Death occurring from 36 hours to one month after surgery. Method of measurement: Phone Follow up.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Farzannejad

Yazd University of Medical Sciences

elhamfarzannejad@yahoo.com+98 35 3623 7273

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026