Comparison of the Efficacy of Reverse Drilling and Traditional Extraction Drilling in Improving Outcomes Following Arthroscopic Anterior Cruciate Ligament Reconstruction: A Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200305046700N8

Enrollment

Registered

2025-09-22

Start date

2025-10-07

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACL reconstruction. Other spontaneous disruption of anterior cruciate ligament of knee

Interventions

Intervention 1: Intervention group: Reverse Driling for ACL reconstruction. Intervention 2: Control group: Traditional Extraction Drilling for ACL reconstruction.

Eligibility

Sex/Gender

All

Age

25 Years to 75 Years

Inclusion criteria

Inclusion criteria: 25 to 75 years old Patients with definite anterior cruciate ligament injuries based on imaging or intraoperative arthroscopy (Sherman grades II and III). Patients with a surgical plan up to 45 days after injury. Having basic literacy skills and the ability to communicate without limitations. Having a smartphone and the ability to use messaging apps Providing written informed consent and complying with the conditions of the GCP (Good Clinical Practice) protocol.

Exclusion criteria

Exclusion criteria: Associated with other knee injuries (posterior cruciate ligament injury, patellar dislocation, osteoarthritis, etc.). Suffering from immune system diseases. The presence of other knee diseases or inflammations such as osteoarthritis, cervical spondylosis, rheumatoid arthritis, etc. Receiving topical hormone injection treatment in the past 3 months. Participation in other clinical trials Cardiovascular, pulmonary, endocrine, metabolic, or other serious diseases that affect patient survival. Severe liver or kidney abnormalities. Patients with viral hepatitis, infectious diseases, or coagulation disorders. Pregnant or lactating women or women who intend to become pregnant during the follow-up period. Patients with severe neurological or psychiatric disorders. Alcohol or drug abuse. Vulnerable groups such as the mentally ill, the terminally ill, the illiterate, and children.

Design outcomes

Primary

Measure	Time frame
IKDC knee joint assessment. Timepoint: 3 and 6 months post surgery. Method of measurement: filling the form.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Razzaghof

Tehran University of Medical Sciences

m.razzaghof@gmail.com+98 21 6658 0196

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026