Lateral screw in high tibial osteotomy

Evaluating the efficacy and side effects of using lateral screw in high tibial osteotomy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200305046700N6

Enrollment

Registered

2025-05-03

Start date

2025-05-20

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Osteoarthritis of knee

Interventions

Intervention 1: Intervention group: HTO with screw. Intervention 2: Control group: HTO without screw.

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age >18 and <50 Varus knee with or without medial osteoarthritis (Kellgren-Lawrence grade 3–4) Informed consent MPTA = 83

Exclusion criteria

Exclusion criteria: Previous limb surgery Inflammatory arthritis Range of motion 15°, flexion contracture >15°, or tibial subluxation >1 cm Severe medial tibial bone loss (>3 mm)

Design outcomes

Primary

Measure	Time frame
Improvement in knee function and pain based on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score. Timepoint: WOMAC score will be assessed at baseline (preoperative), 6 months after surgery. Method of measurement: The Persian-validated version of the WOMAC questionnaire will be used. The questionnaire will be self-reported by the patient under supervision of the research team.	—

Measure

Time frame

Improvement in knee function and pain based on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score. Timepoint: WOMAC score will be assessed at baseline (preoperative), 6 months after surgery. Method of measurement: The Persian-validated version of the WOMAC questionnaire will be used. The questionnaire will be self-reported by the patient under supervision of the research team.

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Secondary

Measure	Time frame
Pain level during activity using Visual Analog Scale (VAS). Timepoint: Preoperative, 6 weeks, 12 weeks, 6 months, and 1 year after surgery. Method of measurement: VAS questionnaire (0–10 scale), patient-reported.;Radiographic union of the osteotomy site after high tibial osteotomy (HTO). Timepoint: 6 weeks, 8 weeks, 10 weeks, 12 weeks, 6 months, and 1 year. Method of measurement: Radiographic assessment by orthopedic surgeon. Union is confirmed when 3 out of 4 cortices are bridged on standard AP and lateral X-rays and the patient reports minimal or no pain during full weight-bearing (VAS = 2).;Time (in weeks) to return to work and athletic activity. Timepoint: Recorded once achieved during follow-up. Method of measurement: Patient interview during follow-up visits.;Radiological Angles (MPTA, LDFA, PTS, Varus Angle). Timepoint: Preoperative and last follow-up (6 months or 1 year). Method of measurement: Radiographic measurement on full-length standing X-rays.	—

Measure

Time frame

Pain level during activity using Visual Analog Scale (VAS). Timepoint: Preoperative, 6 weeks, 12 weeks, 6 months, and 1 year after surgery. Method of measurement: VAS questionnaire (0–10 scale), patient-reported.;Radiographic union of the osteotomy site after high tibial osteotomy (HTO). Timepoint: 6 weeks, 8 weeks, 10 weeks, 12 weeks, 6 months, and 1 year. Method of measurement: Radiographic assessment by orthopedic surgeon. Union is confirmed when 3 out of 4 cortices are bridged on standard AP and lateral X-rays and the patient reports minimal or no pain during full weight-bearing (VAS = 2).;Time (in weeks) to return to work and athletic activity. Timepoint: Recorded once achieved during follow-up. Method of measurement: Patient interview during follow-up visits.;Radiological Angles (MPTA, LDFA, PTS, Varus Angle). Timepoint: Preoperative and last follow-up (6 months or 1 year). Method of measurement: Radiographic measurement on full-length standing X-rays.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Razzaghof

Tehran University of Medical Sciences

m-razzaghof@razi.tums.ac.ir+98 21 6658 0196

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026