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Comparison of Adhesive Pharmacological Form of Achillea Millefolium with Triamcinolone Acetonide Effects in Treating the Symptoms and Reducing Period of Recurrent Aphthous Stomatitis

Comparison of Achillea Millefolium with Triamcinolone Acetonide Mucoadhesive Film Effects in Treating the Symptoms and Reducing Period of Recurrent Minor Aphthous Stomatitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200303046685N3
Enrollment
60
Registered
2022-04-11
Start date
2021-11-22
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent minor Aphthous stomatitis. Recurrent oral aphthae

Interventions

Intervention 1: First intervention group: Achillea millefolium adhesive film, every day after every meal and before bed, the duration of treatment for a week or until the lesions heal, whichever occur

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 50 Years

Inclusion criteria

Inclusion criteria: patients in the age group of 16 to 50 years with a minor oral stomititis that has been diagnosed by an oral disease specialist. No more than 24 hours after the onset of the minor oral stomatitis.

Exclusion criteria

Exclusion criteria: Pregnancy and lactation concomitant treatment with other drugs allergy to herbs or triamcinolone immunodeficiency current and past head and neck radiotherapy and current chemotherapy neuropsychiatric disorders and lack of cooperation systemic steroid, Immune regulators and non-steroidal anti-inflammatory drugs users Patients with a history of ulcerative colitis Behcet's disease, severe anemia and Crohn's disease

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: Days two, four and six of the study. Method of measurement: VAS ( visual analogue scale).;The size of the aphthous lesion. Timepoint: Days two, four and six of the study. Method of measurement: ruler (millimeter).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFahimeh Pakravan

Esfahan University of Medical Sciences

pakravan@dnt.mui.ac.ir+98 31 3436 8793

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026