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Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200302046669N1
Enrollment
37
Registered
2021-06-12
Start date
2021-06-10
Completion date
Unknown
Last updated
2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infraorbital dark circle. Chloasma of eyelid and periocular area

Interventions

Intervention 1: Intervention group: Microneedling to a depth of 2 to 3 mm of the skin with tranexamic acid 3 times at intervals of 2 weeks on one side under the eye. Random selection. Intervention 2:

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: People 18 to 50 years old with dark circles around the eyes

Exclusion criteria

Exclusion criteria: Pregnant women and breastfeeding mothers Taking oral contraceptive pills during the last 12 months and during the study Existence of any history of coagulation disorders and thrombotic problemsCommunity Verified icon Taking anticoagulants Existence of allergy to the studied drugs and topical lidocaine History of dark circles treatment around the eyes during the last six months Hereditary or acquired connective tissue diseases History of colloidal scarring History of isotretinoin use within one year before treatment

Design outcomes

Primary

MeasureTime frame
Percentage of improvement of opacity after 3 sessions of treatment. Timepoint: It is done at the beginning of the study and weeks 2, 4, 8 and 12. Method of measurement: ??? ?????? ?? ??????.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Badakhsh

Ahvaz University of Medical Sciences

badakhsh_f@yahoo.com+98 61 3337 4866

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026