Assessing the effect of fluid therapy with either normal saline or dextrose half saline on blood glucose and plasma electrolyte levels in neonatal surgery

Comparative study of two fluid therapy methods with either normal saline or DW5% NaCl 0.45% effect on blood glucose and plasma electrolyte levels during and after neonatal surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200229046645N1

Enrollment

Registered

2020-04-14

Start date

2020-03-19

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vital signs during neonatal surgery, Mean serum sodium and bicarbonate during neonatal surgery, Mean acidity and base excess during neonatal surgery, Blood glucose level during neonatal surgery.

Interventions

Intervention 1: Intervention group A: Patients who receive 10 cc per kilogram body weight normal saline as serum therapy during the surgery. Intervention 2: Intervention group B: Patients who receive

Eligibility

Sex/Gender

All

Age

1 Days to 30 Days

Inclusion criteria

Inclusion criteria: Candidate for surgery under general anesthesia ASA=1,2 Parental consent of the patients to participate in the study

Exclusion criteria

Exclusion criteria: Presence of any underlying disease in the neonate

Design outcomes

Primary

Measure	Time frame
Sodium and bicarbonate serum levels. Timepoint: Beginning of the surgery, End of the surgery, 2 hours after the surgery. Method of measurement: Blood sample.;Serum acidity and base excess. Timepoint: End of the surgery. Method of measurement: Blood sample.;Vital signs. Timepoint: Beginning of the surgery, 15th minute of the surgery, 30th minute of the surgery. Method of measurement: Patient monitoring machine.	—

Measure

Time frame

Sodium and bicarbonate serum levels. Timepoint: Beginning of the surgery, End of the surgery, 2 hours after the surgery. Method of measurement: Blood sample.;Serum acidity and base excess. Timepoint: End of the surgery. Method of measurement: Blood sample.;Vital signs. Timepoint: Beginning of the surgery, 15th minute of the surgery, 30th minute of the surgery. Method of measurement: Patient monitoring machine.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegin Khavarian moghadam

Esfahan University of Medical Sciences

negin.khavarian@gmail.com+98 87 3362 2634

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026