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Investigating the effect of commiphora mukul on osteoarthritis of the knee

Evaluation of the effectiveness of Iranian traditional medicine product based on commiphora mukul on patients with osteoarthritis of the knee compared to placebo

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200225046612N1
Enrollment
70
Registered
2020-05-01
Start date
2020-05-21
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoartritis. Primary generalized osteoarthrosis

Interventions

Intervention 1: Intervention group: twice a day for two months from the extract of commiphora mukul plant, which is prepared by Badrang teb Kuhistan, affiliated to the Science and Technology Park of t

Sponsors

Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients should be between 40 and 70 years old, Diagnosis of knee osteoarthritis based on the diagnostic criteria of American College of Rheumatology and confirmation of knee osteoarthritis by a rheumatologist using radiography and kellgren lawrence criteria The presence of moderate knee pain in the last 24 hours so that according to the Visual Analogue Scale (VAS) the pain is between 4 to 7 cm

Exclusion criteria

Exclusion criteria: .Cancer or serious illness Symptoms or history of liver or kidney failure Treatment with oral corticosteroids in the last 4 weeks or Corticosteroid injections in the last 6 months fever Consumption of any type of medicinal plant Allergy to commiphora Lack of willingness to continue participating in the study Nonconformity with the study protocol See any side effects Lack of nutritional supplementation and painkillers

Design outcomes

Primary

MeasureTime frame
Quality of Life. Timepoint: Before the intervention and the next two months. Method of measurement: Koos questionnaire.;Inability to function. Timepoint: Before the intervention and the next two months. Method of measurement: Koos questionnaire.;The severity of the pain. Timepoint: Before the intervention and the next two months. Method of measurement: VAS questionnair.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMirzaie abolghasem

Kermanshah University of Medical Sciences

abolghasem.mirzaie@gmail.com0098838214440

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026