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Repetitive transcranial magnetic stimulation in psychological non-epileptic seizure

Evaluation of the efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with functional neurological symptoms (psychological non-epileptic seizure subtype)

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200225046611N1
Enrollment
30
Registered
2020-04-01
Start date
2020-04-05
Completion date
Unknown
Last updated
2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional neurological symptom disorder (Psychogenic non-epileptic seizure subtype). Conversion disorder with motor symptom or deficit

Interventions

Intervention 1: Intervention group: Stimulation with rTMS Variant 2 from NEROSOFT Russia company by 10 Hz frequency, 12 sessions for one month, 25 minutes per session, 1200 stimulations per day, with

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years old with psychological non-epileptic seizure based on DSM5

Exclusion criteria

Exclusion criteria: True seizure or epileptiform changes in electroencephalographic long term monitoring Suicide thought Use of Lowering seizure threshold drugs Risk of new suicide attempt Psychosis Personal or family history of seizure Metal objects within 30 cm of the coil such as: aneurysm clips, cervical or cerebral stents, cardiac pacemaker or defibrillators, cochlear implants, Face tattoo using magnetic field sensitive ink

Design outcomes

Primary

MeasureTime frame
Psychological non-epileptic seizures severity. Timepoint: At the beginning of the study (before the intervention), immediately after the intervention and two months later. Method of measurement: Clinical Global Impression.

Secondary

MeasureTime frame
Depressive severity. Timepoint: At the beginning of study(before intervention), immediately after intervention and two months later. Method of measurement: Beck's depression inventory.;Quality of life. Timepoint: At the beginning of study(before intervention), immediately after intervention and two months later. Method of measurement: WHO Quality of Life-BREF.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Arbabi

Tehran University of Medical Sciences

arbabimo@tums.ac.ir+98 21 6119 2421

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026