Erosive oral lichen planus. Lichen planus
Conditions
Interventions
Intervention 1: Intervention group: Chracteristics of the consumed substance: Echinacea herbal tablets, The chemical composition and its concentration: Each tablet contains 114 mg of dried extract of
Consumption frequency: Three times a day orally, Consumption Duration: 35 days. one spoon of mouthwash: nystatin 100000 U/G 20-25 drops,4 ampule betamethasone suspension ,aluminium MG 1 spoon, diphen
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Patients sufering from erosive oral lichen planus refered to isfahan dental school department of oral medicine whose lesions are clinically and pathologically confirmed according to WHO criteria Certaining of the patient's cooperation and consent presence of at least one lichen planus lesion in oral cavity according to modified Thongprasom criteria the clinical score must be more than 1
Exclusion criteria
Exclusion criteria: patients attended another clinical trial in past 3 months pregnancy and lactation presence of lichenoid reactions presence of extraoral lesions use of systemic steroid drugs, analgesics, immunomodulation drugs, NSAIDs a week before trial presence of other lesions in oral cavity history of asthma and allergy patients suffering from systemic conditions such as diabetes, TB, high blood pressure, life threatening diseases and cancer patients suffering from ulcerative colitis, entrogastric diseases, crohns syndrome, behjet`s syndrome, intensive anemia, rheumatoid arthritis, lupus, multiple sclerosis, collagen disorders, leukosis and AIDS history of organ transplantation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion size. Timepoint: At baseline(before intervention),10,25 and 35 days after using Echinacea tablets. Method of measurement: graph paper and ruler.;Pain level. Timepoint: At baseline(before intervention),10,25 and 35 days after using Echinacea tablets. Method of measurement: Visual Analogue Scale index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of lesion healing. Timepoint: At baseline(before intervention),10,25 and 35 days after using Echinacea tablets. Method of measurement: day.;Duration of pain relief. Timepoint: At baseline(before intervention),10,25 and 35 days after using Echinacea tablets. Method of measurement: day. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Saberi
Esfahan University of Medical Sciences
Outcome results
None listed