Effect of soybean and fish liver oil on control of hot flashes, sexual disorders and sleep disorders

The effect of Soybean and Fish oil tablets on control of hot flash, sexual and sleep disorders in pre-menopausal and menopausal women 45-64 years old

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200222046584N1

Enrollment

159

Registered

2020-03-19

Start date

2018-10-02

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause. Menopausal and female climacteric states

Interventions

Intervention 1: Intervention group one: Patients receive soy pills. Intervention 2: Intervention group: Patients receive fish liver oil pills. Intervention 3: Control group: They dont receive any drug

Eligibility

Sex/Gender

Female

Age

45 Years to 64 Years

Inclusion criteria

Inclusion criteria: Ages between 45 and 64 years Not allergic to soy and fish liver pills Having informed consent for inclusion

Exclusion criteria

Exclusion criteria: Lack of reading and writing skills and unable to answer questions No phone calls to follow up Having a history of more than 10 years of menopause Concomitant use of sulfanamides, methotrexate, triamethrenone, sulfasalazine, estrogen, phenytoin, anti-anxiety and antidepressants, daily chemicals and multivitamins, aspirin and painkillers Hormone therapy and OCP use over the past 3 months Use of complementary herbs to remove vasomotor symptoms over the past month Contraindications to hormone therapy include suspected or diagnosed cancer

Design outcomes

Primary

Measure	Time frame
Comparison of the effect of soy tablets and fish liver oil on TSH level. Timepoint: Before and after the intervention. Method of measurement: TSH measurement in blood.;Comparison of the effect of soy and liver oil pill on lipid profile. Timepoint: Before and after the intervention. Method of measurement: lipid profile measurement in blood.;Measuring the number of hot flashes. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.;Measuring the number of times a patient wakes up. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.;Patient's sexual reluctance. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.;Vaginal dryness. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.	—

Measure

Time frame

Comparison of the effect of soy tablets and fish liver oil on TSH level. Timepoint: Before and after the intervention. Method of measurement: TSH measurement in blood.;Comparison of the effect of soy and liver oil pill on lipid profile. Timepoint: Before and after the intervention. Method of measurement: lipid profile measurement in blood.;Measuring the number of hot flashes. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.;Measuring the number of times a patient wakes up. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.;Patient's sexual reluctance. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.;Vaginal dryness. Timepoint: Before and after the intervention. Method of measurement: Patient MRS questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBahareh Pourzand

Iran University of Medical Sciences

bahareh.purzand@yahoo.com+98 21 8670 2503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026