Skip to content

Effect of acetaminophen in patent ductus arteriosus

Effect of prophylactic oral administration of acetaminophen on patent ductus arteriosus(PDA) closure in preterm neonate admitted in NICU section of Ali ibn Abitaleb Hospital in Zahedan in 2019-2020

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200218046538N1
Enrollment
106
Registered
2020-03-10
Start date
2019-10-23
Completion date
Unknown
Last updated
2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent ductus arteriosus. Other congenital malformations of cardiac chambers and connections

Interventions

Intervention 1: Intervention group: premature babies with gestational age less than 32 weeks and weight less than 1500 g inter to study Then, from the first day of birth, oral acetaminophen will be gi

Sponsors

Zahedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Days to 5 Days

Inclusion criteria

Inclusion criteria: All of preterm neonat Gestational ??? less than 32 week Weight less than 1500 gram

Exclusion criteria

Exclusion criteria: Congenital heart disease Major congenital anomaly Use of NSAID in pregnancy with mother Persistant pulmonary hypertention APGAR scor less than 5 Vomitting or hematemesis G6PD deficency Sepsis Intra ventricular hemorrage Urin out put less than 1 cc/kg/hr Cr more than 1/8 mg/dl Plt less than 50000 NEC

Design outcomes

Primary

MeasureTime frame
Percentage of patent ductus arteriosus closure in preterm infants. Timepoint: Percentage of patent ductus arteriosus closure in preterm infants on fifth day of birth. Method of measurement: Echocardiography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Baghiei

Zahedan University of Medical Sciences

Som_baghiei1365@vatanmail.ir+98 51 4261 4781

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026