Depression. Major depressive disorder, recurrent, mild
Conditions
Interventions
Intervention 1: Intervention group: Patients in this group will be evaluated for depression severity through Depression, Anxiety and Stress Scale - 21 (DASS-21) questionnaire and serum BDNF through E
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 65 years Having Major Depression Referring to the 505 Artesh Hospital Treated only with sertraline Moderate to severe depression Having the written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Failure to take medication regularly Drug intolerance Allergy to Nigella sativa Having systemic diseases Pregnancy or breastfeeding in women Tendency to leave during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: At the beginning of the intervention and 6 weeks after treatment. Method of measurement: Using Depression, Anxiety and Stress Scale - 21 (DASS-21).;Serum levels of Brain-Derived Neurotrophic Factor (BDNF). Timepoint: At the beginning of the intervention and 6 weeks after treatment. Method of measurement: By enzyme-linked immunosorbent assay (ELISA) kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Donyavi
Artesh University of Medical Sciences
Outcome results
None listed