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Evaluation of the effects of misoprostol and letrozole in therapeutic abortion

Comparison of the effect of misoprostol and letrozole in the first-trimester abortion of patients referring to Ganjavian Hospital in Dezful in 1400

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200217046521N1
Enrollment
75
Registered
2021-10-03
Start date
2021-09-21
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

medical abortion. Medical abortion

Interventions

Intervention 1: Control group: Group A patients in whom abortion will be performed with vaginal and oral misoprostol are given two 200 µg misoprostol tablets orally (sublingually) and two vaginally in

Sponsors

Dezfoul University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Hemoglobin level greater than 10 gr / l Diastolic pressure less than 95 mmhg Serum hcg level less than 3000 iu / l Gestational age less than 14 weeks

Exclusion criteria

Exclusion criteria: Use of abortion drugs in the last three months itching during pregnancy Existence of adrenal disorders Porphyria, steroid-related cancer, acute or chronic liver disease or thromboembolism History of chronic lung diseases such as asthma, bronchitis, bronchiectasis known allergy to letrozole or misoprostol Breast feeding Multipfetal pregnancy More than two previous cesarean sections uterine surgery and myomectomy contraindications to the letrozol and mosoprostol Existence of intrauterine devices (IUD) Uncontrolled seizures Coagulation disorder or use of anticoagulants Active liver disease, cardiovascular disease Adrenal disease Consumption of glucocorticoids

Design outcomes

Primary

MeasureTime frame
Fetus abortion. Timepoint: Before and after abortion. Method of measurement: Eight hours after the intervention, and every twenty-four hours up to three days if the abortion doesn't occur.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactvahid.kheirandish

Dezfoul University of Medical Sciences

vahid.kheirandish40@gmail.com+98 71 4452 7941

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026