cerebrovascular accident.
Conditions
Interventions
Intervention 1: Intervention group: A single dose of vitamin D3, 300,000 units, IM. 1 ml vial .Manufacturing by DarouPakhsh factory. Intervention 2: Control group: Does not receive intervention (does
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with moderate stroke (NIHSS 5-15) Age between 18 to 65 years Vitamin D levels less than 30 ng/ml
Exclusion criteria
Exclusion criteria: Hypercalcemia (Ca > 10.5 mg/dl) Patients treated with corticosteroids, NSAIDs, statins History of diseases such as cancer, autoimmune disorders, liver diseases Pregnancy and breastfeeding History of allergy to vitamin D Poor chance of survival
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL1-ß. Timepoint: Before intervention and 3rd day after intervention. Method of measurement: Elisa kit.;Neutrophil to Lymphocyte Ratio (NLR). Timepoint: First to 7th day of the study on daily routine. Method of measurement: Calculating the ratio of Neutrophils to Lymphocytes using CBC test.;Platelet to Lymphocyte Ratio (PLR). Timepoint: First to 7th day of the study on daily routine. Method of measurement: Calculating the ratio of Platelet to Lymphocytes using CBC test.;National Institutes of Health Stroke Scale (NIHSS). Timepoint: First to 7th day of the study on daily routine. Method of measurement: Patient medical file.;Barthel Score. Timepoint: Three months after discharge. Method of measurement: Questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lenght of ICU stay. Timepoint: Daily. Method of measurement: Patient file.;Duraton of Mechanical Ventilation. Timepoint: Daily. Method of measurement: Patient file.;28-day mortality. Timepoint: 28th day of hospitalization. Method of measurement: Patient file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaied Amniati
Shahid Beheshti University of Medical Sciences
Outcome results
None listed