Skip to content

Effect of PRP in treatment of anosmia

Evaluation the effectiveness of platelet-rich plasma in smell Improvement of Patients with nasal polyposis due to chronic sinusitis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200211046464N1
Enrollment
24
Registered
2020-05-04
Start date
2017-09-23
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Nasal Polyp. Condition 2: Anosmia. Nasal polyp Anosmia

Interventions

Intervention 1: Intervention group: Patients in both groups underwent sinus endoscopic surgery by only one specific ENT specialist. At this stage, in the intervention group, a platelet-rich plasma was

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age between 15 and 50 years Having chronic sinusitis with polyps Anosmia lasts less than 2 years Existence of anosmia confirmed by olfactory diagnosis test

Exclusion criteria

Exclusion criteria: Suffering from systemic diseases such as diabetes mellitus, Parkinson's and Alzheimer's smoking Head injury history Previous surgical history of paranasal sinuses Congenital anosmia

Design outcomes

Primary

MeasureTime frame
Olfactory score less than 6 in the Iranian Smell Identification Test. Timepoint: Measurement of olfactory score at the beginning of the study (before the intervention), After receiving oral treatment and 3 months after surgery and injection of platelet-rich plasma. Method of measurement: Iranian Smell Identification Test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Mohammadi

Shahid Beheshti University of Medical Sciences

Dr.md.mohammadi@gmail.com+98 21 4483 3279

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026