The efficacy of Ventolin and Pulmicort and normal saline in treatment of bronchiolitis

The comparison of efficacy of nebulized Ventolin and Pulmicort and normal saline in treatment of children under 2 years old with bronchiolitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200209046435N1

Enrollment

100

Registered

2020-03-11

Start date

2020-04-03

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiolitis. Acute bronchiolitis

Interventions

Intervention 1: Intervention group: Ventolin nebulizer (Salbutamol) 0.15 mg/kg every 4 hours will be administered by nebulizer. Intervention 2: Intervention group: Budesonide (Pulmicort) 125 mg 2 twic

Eligibility

Sex/Gender

All

Age

No minimum to 24 Months

Inclusion criteria

Inclusion criteria: Children less than 24 months, , Definitive diagnosis of bronchiolitis Parents’ consent to participate in the study

Exclusion criteria

Exclusion criteria: Chronic heart and lung disease (heart failure or pulmonary cyst) Immunodeficiency Metabolic or neurological diorders Birth below 34 weeks Use of ventilator in neonatal period Receiving systemic corticosteroid or antibiotic during hospitalization

Design outcomes

Primary

Measure	Time frame
Symptom severity (clinical score). Timepoint: Everyday, before intervention and during the intervention. Method of measurement: According to Respiratory Distress Assessment Index (RDAI).;Duration of symptom recovery. Timepoint: Daily, before intervention until the end of intervention. Method of measurement: Duration of recovery from wheezing and cough based on clinical examination.;Oxygen saturation. Timepoint: Every day, before intervention and during the intervention. Method of measurement: Using pulse oximeter.	—

Measure

Time frame

Symptom severity (clinical score). Timepoint: Everyday, before intervention and during the intervention. Method of measurement: According to Respiratory Distress Assessment Index (RDAI).;Duration of symptom recovery. Timepoint: Daily, before intervention until the end of intervention. Method of measurement: Duration of recovery from wheezing and cough based on clinical examination.;Oxygen saturation. Timepoint: Every day, before intervention and during the intervention. Method of measurement: Using pulse oximeter.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarhad Abolnezhadian

Ahvaz University of Medical Sciences

abolnezhadian-f@ajums.ac.ir+98 61 3001 3374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026