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Efficacy of galantamine on cognitive performance

Efficacy of galantamine on cognitive performance of patients under electro convulsive therapy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200207046404N1
Enrollment
75
Registered
2020-04-23
Start date
2018-10-01
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Schizophrenia. Condition 2: Schizoaffective. Condition 3: Mood disorders. Condition 4: Obsessive- compulsive disorders. Schizophrenia Schizoaffective disorders Mood disorder due to known physiological condition with mixed features Obsessive-compulsive disorder

Interventions

Intervention 1: Galantamin 4mg capsules BID in the intervention group until the end of ECT treatment.(for 15 days). Intervention 2: Control group: received placebo capsules BID until the end of ECT t

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged between 18-60 years Patients or their legal guardian must sign an informed consent form Number of sessions of ECT between 4-8

Exclusion criteria

Exclusion criteria: Alcohol & drug abuse or dependence Renal failure Ischemic heart disease Stroke in last 6 months Delirium &Dementia Pregnancy & Lactation History of using Galantamine in past 3 months Galantamine sensitivity Mental retardation

Design outcomes

Primary

MeasureTime frame
Memory. Timepoint: 1day before begining and after session 3 and after the electroconvulsive therapy. Method of measurement: Wechsler, mini mental statuse examination.

Secondary

MeasureTime frame
Nausea. Timepoint: During intervention( once a day for 15 days). Method of measurement: Patient self report.;Confusion. Timepoint: During intervention(once a day for 15 days). Method of measurement: Patient self report.;Dizziness. Timepoint: During intervention(once a day for 15 days). Method of measurement: Patient self report.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHojat Esfandiyary

Sanandaj University of Medical Sciences

Esfandyari@gmail.com+98 87 3362 6968

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026