Comparing the analgesic effect of fluoxetine and vitamin E with vitamin E only in breast pain due tofibrocystic breast disease

Comparing the analgesic effect of fluoxetine and vitamin E with vitamin E only in mastalgia due tofibrocystic breast disease

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200205046381N1

Enrollment

Registered

2020-02-28

Start date

2020-03-20

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mastalgia. Fibroadenosis of breast

Interventions

Intervention 1: Intervention group: receive 600 units of vitamin E daily and 10 mg of fluoxetine per oral for 8 weeks. All drugs are manufactured by Tehran Drug Company. Intervention 2: Control group:

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women 20 to 50 years old with fibrocystic breast disease-induced mastalgia Women with mastalgia criterion equal to or greater than four on the VAS scale Women whose pain lasts more than 5 days per month The patient has no known history of brest disease or malignancy

Exclusion criteria

Exclusion criteria: Women with physical and mental illnesses such as polycystic ovary disease Obese female patients 30=BMI Women who have been on hormone therapy for the past three months Women who use contraceptives

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Baseline and two months after intervention. Method of measurement: VAS Questionaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSheida Shabanian

Shahre-kord University of Medical Sciences

shabanian@skums.ac.ir009832220016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Aug 12, 2026