Ozone therapy and routine medical treatment efficacy on serum level changes of TNF-a and CRP as well as neurological improvement

Comparison of ozone therapy and routine medical treatment efficacy on serum level changes of TNF-a and CRP as well as neurological improvement in recovery period in patients with ischemic stroke

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200202046342N1

Enrollment

Registered

2020-03-03

Start date

2018-11-22

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke. Transient cerebral ischemic attacks and related syndromes

Interventions

Intervention 1: Control group: Receive normal medicine.Serum levels of TNF-a and hs-CRP will also be determined by ELISA with the US-based kit ELISA by eBioscience Iranian company Amines. Intervention

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Being in the phase of ischemic stroke rehabilitation (NIHSS <15- mRs <5) and being alert to cooperate in the implementation of the plan At least 2 months have passed since the onset of acute stroke

Exclusion criteria

Exclusion criteria: Hemorrhagic stroke Cancer Active infection

Design outcomes

Primary

Measure	Time frame
Serum levels of TNF-a and hs-CRP. Timepoint: Patients in the first group (control group) will receive the medication on the first day and will receive physiotherapy. After 90 days, serum levels of TNF-a and hs-CRP were also determined by ELISA. Method of measurement: Serum TNF-a and hs-CRP levels were also determined by ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Hadi Hoseinipour

Kashan University of Medical Sciences

hoseinipour-sh@mail.kaums.ac.ir+98 31 5550 0111

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026