Lactic acidosis. Atherosclerotic heart disease
Conditions
Interventions
Intervention 1: Intervention group: We continue to prescribe metformin before the angiography and up to 48 hours after the angiography.During these 48 hours, we follow up the patients and measure thei
Sponsors
Alborz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patient with type 2 diabetes who has undergone coronary angiography The GFR before angiography is equal to or greater than 60 ml per minute Patient with diabetes with a history of metformin usage Patient's Ejection Fraction is equal to or greater than 45% Patient's systolic blood pressure is equal to or greater than 90 mm Hg Serum creatinine levels before angiography are less than 1.49 mg in males and less than 1.40 mg / ml in females The patient's plasma pH should be 7.45-7.35 before angiography
Exclusion criteria
Exclusion criteria: Critical physical condition requires immediate intervention Failure to perform PH or creatinine sampling and lactate levels after angiography Sepsis and other conditions that cause lactic acidosis Discontinuation of metformin usage by the patient Diarrhea, vomiting, and other conditions that predispose the patient to dehydration Increase serum creatinine by more than 1.5 mg / dL
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lactic acidosis. Timepoint: Before the intervention and after coronary angiography up to 48 hours. Method of measurement: blood sampling. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Jalali
Alborz University of Medical Sciences
Outcome results
None listed