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Comparison of effect of oral Utrogestan and intramascular Proluton on Maternal and fetal Doppler circulatuion in women with preterm labor risk

Comparison of effect of oral Utrogestan and intramascular Proluton on Maternal and fetal Doppler circulatuion in women with preterm labor risk

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200201046324N1
Enrollment
152
Registered
2020-05-05
Start date
2019-12-07
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm labor. Preterm labor without delivery, unspecified trimester

Interventions

Intervention 1: Intervention group: Oral progesterone group (UTROGESTAN 200 mg made by BUSINESS [France], importer of Behin Pad) twice a day for 48 hours. Intervention 2: Intervention group: Muscle pr

Sponsors

Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Single pregnancy with gestational age of 20-34 weeks based on LMP and ultrasound confirmation who presented with pain and consent to participate in the study Cervical length shortening (less than 25 mm) No rupture of membrane Preterm labor history Experience regular uterine contractions at least one occasion leading to an episode of hospitalization for preterm labor Changes in cervical dilatation or effacement confirmed by vaginal ultrasound No maternal hypertension

Exclusion criteria

Exclusion criteria: No follow-up for Doppler ultrasound No proper use of medications Known fetal anomaly and fetal death Tocolytic therapy Progesterone allergy Indications of rapid labor such as fetal distress or severe bleeding

Design outcomes

Primary

MeasureTime frame
Pulsatility Index (PI). Timepoint: At baseline and 48 hours later. Method of measurement: Abdominal ultrasound transducer 2-5 MHz.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Mesdaghinia

Kashan University of Medical Sciences

mesdaghinia-e@kaums.ac.ir+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026