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Comparison of the effect of DiphenCiprone alone and DiphenCiprone with intralesional injection of platelet-rich plasma in alopecia areata

Comparative evaluation of the response rate based on tricoscopic criteria in patients with severe alopecia areata treated with diphencyprone with or without intralesional platelet rich plasma

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200130046311N1
Enrollment
20
Registered
2021-04-13
Start date
2020-02-29
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alopecia areata. Other alopecia areata

Interventions

Intervention 1: Intervention group: taking Diphen Ciprone and platelet-rich plasma together. All patients participating in the study received diphen cyprone and PRP simultaneously on one side of their

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: A patient with alopecia areata whose definitive diagnosis was made on clinical or histological basis and their involvement was severe (> 50% scalp area and less than 100%). Positive response to test with 2% Diphen Ciprone solution

Exclusion criteria

Exclusion criteria: Patients with alopecia totalis or universalis Receive any systemic treatment during the last 6 months Children under 18 years Pregnant and lactating women Immunosuppressed patient patient with platelet dysfunction patient with a history of injecting steroids on the site over the past month Fever, systemic infection and local infection at the injection site

Design outcomes

Primary

MeasureTime frame
Severity alopecia tool score (SALT score). Timepoint: Trichoscopic evaluation at baseline, 3 months later, 6 months later. Method of measurement: Trichoscope.

Secondary

MeasureTime frame
SALT score evaluation. Timepoint: Evaluation at baseline, 3 months later, 6 months later. Method of measurement: visual evaluation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Rezayat

Tehran University of Medical Sciences

azadehrezayat@gmail.com+98 21 5563 0553

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026