Evaluation the effect of extracts of Cydonia oblonga, Punica granatum and Phyllanthus emblica on the prevention of gastric disease in hospitalized burned patients

Evaluation the Effect of extracts of Cydonia oblonga, Punica granatum and Phyllanthus emblica on the prevention of gastric and peptic ulcer disease in hospitalized burned patients at Ayatollah Taleghani hospital in Ahvaz: double blind clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200128046288N2

Enrollment

Registered

2020-05-16

Start date

2020-06-03

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric reflux and peptic ulcer. Peptic ulcer, site unspecified

Interventions

Intervention 1: Intervention group: In addition to receiving pentoprazole, 30 ml of herbal syrup will be taken twice a day for a week. The herbal syrup includes fruit of Quince, Phyllanthus emblica an

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years of age with a burn rate of 35% or more who are hospitalized for more than ten days. The women in the study had a negative pregnancy test No history of asthma and heart disease (heart block and heart failure)

Exclusion criteria

Exclusion criteria: Patients with a history of endoscopic confirmed peptic ulcer. Gasteric cancer Allergy to plants especially fruits of Quince, Phyllanthus emblica and pomegranate flowers

Design outcomes

Primary

Measure	Time frame
Heartburn. Timepoint: Before and a week after the intervention. Method of measurement: questionnaire.;Bloating. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Feeling of heaviness in the stomach after eating. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Early satiety. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Feeling a bitter liquid (acid) in the throat. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Belching. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.	—

Measure

Time frame

Heartburn. Timepoint: Before and a week after the intervention. Method of measurement: questionnaire.;Bloating. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Feeling of heaviness in the stomach after eating. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Early satiety. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Feeling a bitter liquid (acid) in the throat. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.;Belching. Timepoint: Before and a week after the intervention. Method of measurement: Gastric reflux questionnaire.

—

Secondary

Measure	Time frame
The rate of drug side effects. Timepoint: During drug use. Method of measurement: Patient Report.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFereshteh golfakhrabadi

Ahvaz University of Medical Sciences

golfakhrabadi@yahoo.com+98 61 3373 8378

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026