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Investigating microfat, PRF, and exosomes in facial rejuvenation

A comparative study of the effectiveness of microfat, microfat and PRF, microfat and exosome in facial rejuvenation: A double blind randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N70
Enrollment
10
Registered
2026-01-12
Start date
2026-01-05
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin aging. Atrophic disorder of skin

Interventions

Intervention 1: First intervention group: First intervention patients will receive microfat ??+ Exosome injections in half of the cases. Intervention 2: Control Group One: Control patients will receiv

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 35 to 65 Patient cooperation in carrying out therapeutic interventions and attending all treatment sessions and follow-ups Patient cooperation in making necessary recommendations after performing therapeutic interventions

Exclusion criteria

Exclusion criteria: Received facial rejuvenation treatment within the past 3 months Serious underlying skin and internal disease Taking anticoagulant medications Abnormal blood clotting tests

Design outcomes

Primary

MeasureTime frame
The amount of wrinkles. Timepoint: Before treatment and three months after the start of treatment. Method of measurement: Visio face.

Secondary

MeasureTime frame
Inflammation. Timepoint: After session. Method of measurement: Questionnaire and visit.;Intensity of pain. Timepoint: Treatment time. Method of measurement: Questionnaire and visit.;Side effects. Timepoint: One week after treatment. Method of measurement: Questionnaire and visit.;Patient Satisfaction. Timepoint: Three month after treatment. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

dr.sonazare@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026