Skin aging. Atrophic disorder of skin
Conditions
Interventions
Intervention 1: Intervention group: Patients will receive fibroblast and exosomes drug delivery on the left side of the face after CO2 laser. Intervention 2: Control group: Patients will receive fibro
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 59 Years
Inclusion criteria
Inclusion criteria: Age 30 years and above and less than 60 years Having wrinkles and sagging on the face Written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Patients with malignancy Receiving chemotherapy within the last 5 years Patients with sepsis Pregnancy Breastfeeding Smoking Active wound or infection at the treatment site Those receiving any topical or systemic medication for facial rejuvenation in the last 3 months will be excluded from this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of wrinkles. Timepoint: Before treatment and six months after the start of treatment. Method of measurement: Visio face. | — |
Secondary
| Measure | Time frame |
|---|---|
| Inflammation. Timepoint: After each session. Method of measurement: Questionnaire and visit.;Intensity of pain. Timepoint: Treatment time. Method of measurement: Questionnaire and visit.;Side effects. Timepoint: One week after treatment. Method of measurement: Questionnaire and visit.;Patient satisfaction. Timepoint: Three month after treatment. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSona Zare
Skin and Stem cell Research Center of Tehran University of Medical Sciences
Outcome results
None listed