Review of Stromal Vascular Fraction Gel injections for eye rejuvenation

Investigating the effect of SVF gel (Stromal Vascular Fraction (SVF) + non cross-linked hyaluronic acid) on the periorbital rejuvenation and comparing it with SVF injection alone

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200127046282N59

Enrollment

Registered

2025-12-01

Start date

2025-12-21

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye rejuvenation. Atrophic disorder of skin

Interventions

Intervention 1: Control group: Patients are injected with 2 cc of Stromal Vascular Fraction on one side of the eye area in one session. Intervention 2: Intervention group: Patients undergo injections

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age from 18 to 65 years The patient has aging around the eyes.

Exclusion criteria

Exclusion criteria: Active infection in the facial area Pregnancy Breastfeeding History of cancer

Design outcomes

Primary

Measure	Time frame
The amount of wrinkles. Timepoint: Before and 3 months after the intervention. Method of measurement: Visio face.	—

Secondary

Measure	Time frame
Satisfaction rate. Timepoint: After completing the intervention. Method of measurement: Comparison of the reduction in wrinkles around the eyes of patients after treatment compared to before by the patient herself (score 0 - 10)(feminine).;Inflammation. Timepoint: Half an hour after the end of the intervention. Method of measurement: Visit.;Intensity of pain. Timepoint: At the time of the intervention. Method of measurement: Questionnaire and visit (Score 0 to 10 for pain level).	—

Measure

Time frame

Satisfaction rate. Timepoint: After completing the intervention. Method of measurement: Comparison of the reduction in wrinkles around the eyes of patients after treatment compared to before by the patient herself (score 0 - 10)(feminine).;Inflammation. Timepoint: Half an hour after the end of the intervention. Method of measurement: Visit.;Intensity of pain. Timepoint: At the time of the intervention. Method of measurement: Questionnaire and visit (Score 0 to 10 for pain level).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

dr.sonazare@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026