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Investigation of exosome injection in combination with minoxidil in patients with androgenic hair loss

Safety and effectiveness of fibroblast-derived exosome injection in combination with minoxidil in patients with androgenic hair loss compared to minoxidil alone: ??a randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N54
Enrollment
15
Registered
2024-08-19
Start date
2024-08-21
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenetic alopecia. Androgenic alopecia, unspecified

Interventions

Intervention 1: Intervention group: One side of the patients head is treated with exosome injection (5 sessions at an interval of 3 weeks) and topical minoxidil 5% (15 weeks). Intervention 2: Control

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Age 18 years and above and less than 45 years Hamilton score 2 to 5 in male and female hair loss Complete consent of the patient to participate in the plan

Exclusion criteria

Exclusion criteria: Patients with malignancy Receiving chemotherapy in the last 5 years Patients with sepsis smoking Pregnancy or breastfeeding Active wound or infection at the treatment site Receiving any topical or systemic medication in the last 3 months for hair loss

Design outcomes

Primary

MeasureTime frame
Hair density. Timepoint: before the start of treatment and three and six months after the start of the intervention. Method of measurement: Biometric examination will be done and the findings from VISIOFACE and TES-TB (hair loss type with X1 lens, hair density and scalp condition with X60Triple lens, hair diameter and PORE condition with KPL X150 lens and hair shaft surface condition with X700 lens) It will be recorded for each patient.

Secondary

MeasureTime frame
Side effects. Timepoint: During treatment. Method of measurement: Questionnaire and observation.;Satisfaction. Timepoint: A month after the last session. Method of measurement: Satisfaction Questionnaire and visit.;Tolerability. Timepoint: During treatment. Method of measurement: Questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026