Skip to content

Investigating the safety and efficacy of mesenchymal stem cells secretome injection in female androgenetic alopecia

Investigating the safety and efficacy of Wharton jelly mesenchymal stem cells secretome injection in female androgenetic alopecia (Clinical, Biometric and Histopathological evaluation)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N41
Enrollment
20
Registered
2024-06-09
Start date
2024-06-04
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hair Loss. Nonscarring hair loss, unspecified

Interventions

Intervention 1: Intervention group: For each patient, there are 3 sessions of direct and intradermal conditioned medium injection in the area with hair loss at an interval of 4 weeks. Intervention 2:

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 45 Years

Inclusion criteria

Inclusion criteria: patients with female androgenetic alopecia grade 5 Patients aged 30 to 45 years Hormonally healthy patients

Exclusion criteria

Exclusion criteria: Presence of evidence of sepsis, immunosuppression and cancer Use of oral drug treatment for androgenic hair loss (such as finasteride, dutasteride or any other anti-androgen drug) in 12 months the past Use of local drug treatment of androgenic hair loss (such as minoxidil, prostaglandin analogues, retinoids orCorticosteroids) in the last 12 months Discovering another cause for the patient's hair loss Non-cooperation of the patient until the end of the study

Design outcomes

Primary

MeasureTime frame
The amount of hair loss. Timepoint: Before starting treatment, end of the first, second, third month and one month after the end of the treatment period (end of the fourth month). Method of measurement: Trichoscan.

Secondary

MeasureTime frame
Side effects. Timepoint: Before starting treatment, end of the first, second, third month and one month after the end of the treatment period (end of the fourth month). Method of measurement: Questionnaire and visit.;Effectiveness. Timepoint: Before starting treatment, end of the first, second, third month and one month after the end of the treatment period (end of the fourth month). Method of measurement: Questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026