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Investigating the safety and effectiveness of conditioned medium injection of stem cells in male androgenetic alopecia

Investigating the safety and efficacy of Wharton jelly mesenchymal stem cell conditioned medium injection in male androgenetic alopecia (phase 1 and 2 clinical trial)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N39
Enrollment
40
Registered
2024-06-08
Start date
2024-06-14
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hair Loss. Nonscarring hair loss, unspecified

Interventions

Intervention 1: Intervention group: The patients head will receive 2 cc of conditioning medium 2 times with an interval of 60 days. Intervention 2: Control group: the position of the patients head wil

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 45 Years

Inclusion criteria

Inclusion criteria: Patients with male androgenetic alopecia grade 3-5 Age between 25 and 45 years

Exclusion criteria

Exclusion criteria: Presence of evidence of sepsis immunosuppression and cancer Use of oral drug treatment for androgenic hair loss (such as finasteride, dutasteride or any other anti-androgen drug) in 12 months the past Use of local drug treatment of androgenic hair loss (such as minoxidil, prostaglandin analogues, retinoids or Corticosteroids) in the last 12 months Discovering another cause for the patient's hair loss Non-cooperation of the patient until the end of the study

Design outcomes

Primary

MeasureTime frame
The amount of hair loss. Timepoint: Before starting treatment, end of the first, second, third month and one month after the end of the treatment period (end of the fourth month). Method of measurement: Trichoscan.

Secondary

MeasureTime frame
Side effects (pain, burning, inflammation). Timepoint: Before starting treatment, end of the first, second, third month and one month after the end of the treatment period (end of the fourth month). Method of measurement: Questionnaire and visit.;Effectiveness (increasing the number of hair, increasing the thickness). Timepoint: Before starting treatment, end of the first, second, third month and one month after the end of the treatment period (end of the fourth month). Method of measurement: Questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026