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Evaluation of the effect of nanofat along with SVF and PRP in facial rejuvenation and dark circles around the eyes

Evaluation of the effectiveness of nanofat along with Stromal vascular fraction (SVF) and Platelet Rich plasma (PRP) in facial rejuvenation and dark circles around the eyes

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N31
Enrollment
30
Registered
2023-05-18
Start date
2023-05-20
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: periorbital dark circles. Condition 2: Skin aging. Chloasma of eyelid and periocular area Atrophic disorder of skin, unspecified

Interventions

Intervention 1: Control group 1: In one session, patients are treated with 5 cc of nanofat injection (prepared at the research center clinic) in the whole face and under the eyes. Intervention 2: Cont

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age from 18 to 65 years Patient with periorbital dark circles The patient has wrinkles

Exclusion criteria

Exclusion criteria: Active infection on face Pregnancy Breastfeeding History of cancer structural dark circles or under eye loss of fat

Design outcomes

Primary

MeasureTime frame
Periorbital dark circles. Timepoint: Before, during the treatment and 3 months after intervention. Method of measurement: severity of under eye dark halos in comparison to the rest of the face, using Mexameter device.;The amount of wrinkles. Timepoint: Before treatment and six months after intervention. Method of measurement: Visio face.

Secondary

MeasureTime frame
Satisfaction rate. Timepoint: After completing the intervention. Method of measurement: comparing the severity of periorbital dark circles, before and after treatment (score from 0 - 10).;Inflammation. Timepoint: Half an hour after the end of the intervention. Method of measurement: Questionnaire and visit.;Intensity of pain. Timepoint: At the time of the intervention. Method of measurement: Questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026