Evaluation of clinical improvement of conditioned media of adipose derived stem cells in the treatment of wrinkles in the whole facial skin

Title : Evaluation of clinical improvement of wrinkles in the whole facial skin using radiofrequency microneedling with adipose derived stem cell-conditioned medium

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200127046282N3

Enrollment

Registered

2021-06-06

Start date

2021-07-21

Completion date

Unknown

Last updated

2021-06-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin aging. Atrophic disorder of skin

Interventions

Intervention 1: Control group: (Other side of face) After sufficient anesthesia, first treatment with micro needling, and then physiological serum is applied topically to the site of the wrinkles for

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 20-60 Having middle wrinkles in face region

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding History of cancer Patients with a new history of gel and Botox injections People with Mental Disorders Active infection in the face

Design outcomes

Primary

Measure	Time frame
The amount of wrinkles. Timepoint: Before treatment and one month after the last session. Method of measurement: Visio face.	—

Secondary

Measure	Time frame
Side effects. Timepoint: One week after session. Method of measurement: Questionnaire and visit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2221 5558

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026