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Comparing the effectiveness of two cell products and triamcinolone drug in the treatment of lichen planopillaris

Comparing the effectiveness of conditioned medium derived from Wharton's jelly mesenchymal stem cells, extracellular vesicles derived from Wharton's jelly and triamcinolone in the treatment of lichen Plano Pilaris

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N29
Enrollment
30
Registered
2023-05-06
Start date
2023-05-10
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lichen Planopilaris. Cicatricial alopecia [scarring hair loss]

Interventions

Intervention 1: Control group: 10 patients were injected with 3 cc of triamcinolone (Jaber Ebne Hayyan company) 5 times with a 1-month interval. Intervention 2: Intervention group: 10 patients are inj

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 18-60 years Lichen planopilaris disease has been proven

Exclusion criteria

Exclusion criteria: breastfeeding pregnancy Infectious diseases

Design outcomes

Primary

MeasureTime frame
Response to treatment. Timepoint: 0 and 6 months after the start of the study. Method of measurement: Lichen plano pilaris activity index.;The amount of hair loss. Timepoint: Before starting treatment and one month after the end of the treatment period. Method of measurement: Trichoscan.

Secondary

MeasureTime frame
The level of satisfaction with treatment qualitatively. Timepoint: 2 and 6 months after the start of treatment. Method of measurement: In the qualitative questionnaire (excellent effect, good, medium, low, ineffective).;Side effects. Timepoint: Before starting treatment and one month after the end of the treatment period. Method of measurement: Questionnaire and visit.;Effectiveness. Timepoint: Before starting treatment and one month after the end of the treatment period. Method of measurement: Questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026