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Evaluation of safety and effectiveness of liposomal hyaluronic acid, PRP and vitamin C in rejuvenation and brightening under the eyes

Evaluation of safety and effectiveness of liposomal hyaluronic acid, PRP and vitamin C in rejuvenation and brightening under the eyes

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N28
Enrollment
90
Registered
2023-05-06
Start date
2023-05-10
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Darkening under the eye.

Interventions

Intervention 1: Intervention group: Patients use 1 cc liposomal hyaluronic acid (Zist Sakht Bonyan Pars Company) products topically in the area under the eyes once a day for three months. Intervention

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
21 Years to 60 Years

Inclusion criteria

Inclusion criteria: Darkness and wrinkles in the lower eyelid area, which need to be treated according to the opinion of the hospital doctor and the patient's desire.

Exclusion criteria

Exclusion criteria: Patients who had undergone previous surgery in the eyelid area Have had previous minimally invasive treatments such as botulinum toxin or fillers in the eyelid area. Patients with active skin disorders or inflammation, acute or chronic infection, tumors or cancer Patients under anticoagulant treatment smokers

Design outcomes

Primary

MeasureTime frame
The amount of darkness under the eyes. Timepoint: prior to treatment, three and six months after the last treatment session. Method of measurement: VisioFace device.;The amount of wrinkles under the eyes. Timepoint: prior to treatment, three and six months after the last treatment session. Method of measurement: Visioface.

Secondary

MeasureTime frame
Patient satisfaction. Timepoint: prior to treatment, three months and six months after the last treatment session. Method of measurement: Standard questionnaires visual analogue scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem Cell Research Center, Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026