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Evaluation of autologous cell transplantation without melanocyte-keratinocyte culture in suspension and gel form in the treatment of patients with persistent vitiligo

Evaluation of the efficacy and safety of autologous cell transplantation without melanocyte-keratinocyte culture in suspension and gel form in the treatment of patients with persistent vitiligo: Phase one clinical trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N22
Enrollment
10
Registered
2023-02-05
Start date
2023-02-20
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitiligo. disorders of pigmentation

Interventions

Intervention 1: Intervention group: A diseased patch of patient dermabrade and a gel containing cells is placed on the area and bandaged. Intervention 2: Control group: A patch of patient dermabrade a

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Having no treatment within past 6 months No pregnancy or breast-feeding Have a diagnosis of vitiligo with depigmented patch more than 5 cm despite receiving at least 3 months active treatment No infection at recipient site No history of keloid and or koebner phenomenon No history of active hepatitis the B, C, or AIDS No active uncontrolled chronic systemic disease

Exclusion criteria

Exclusion criteria: Vitiligo patients with active or progressive disease within last 12 months.

Design outcomes

Primary

MeasureTime frame
Repigmentation rate. Timepoint: Before, 1, 3 and 6 months after treatment. Method of measurement: The amount of melanin in the treated areas compared to before treatment using a maxameter device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem Cell Research Center, Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026