The efficacy of PRP, Erbium laser and QS laser in the treatment of periorbital dark circles

Evaluation of simultaneous effect of CO2 laser and QS laser with PRP on periorbital dark circles

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200127046282N20

Enrollment

Registered

2022-06-24

Start date

2022-07-06

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

periorbital dark circles. Chloasma of eyelid and periocular area

Interventions

Intervention 1: Intervention group: In each session, patients are treated with Q-switched Nd:YAG 1064nm laser, deka fractional CO2 laser and 1 cc injection of PRP, three times with an interval of six

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: age from 18 to 65 years patient with periorbital dark circles

Exclusion criteria

Exclusion criteria: Active infection on face Pregnancy Breastfeeding History of cancer structural dark circles or under eye loss of fat

Design outcomes

Primary

Measure	Time frame
Periorbital dark circles. Timepoint: Before, during treatment and 3 months after treatment. Method of measurement: severity of under eye dark halos in comparison to the rest of the face, using Mexameter device.	—

Secondary

Measure	Time frame
Satisfaction rate. Timepoint: After the last session. Method of measurement: comparing the severity of periorbital dark circles, before and after treatment (score from 0 - 10).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026