Evaluation of clinical improvement of conditioned media of adipose derived stem cells in the treatment of wrinkles in the facial skin

Evaluation the effect of adipose derived stem cells conditioned medium (ADSC-CM) on rejuvenation after resurfacing with ablative fractional carbon dioxide laser

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200127046282N19

Enrollment

Registered

2022-06-06

Start date

2022-06-20

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin aging. Atrophic disorder of skin

Interventions

Intervention 1: Intervention group: After adequate anesthesia, a group is first treated with laser and then the stem cells conditioned medium is applied topically to the wrinkle site for one hour. Thi

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 20-60 Having middle wrinkles in face region

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding History of cancer Patients with a new history of gel and Botox injections People with Mental Disorders Active infection in the face

Design outcomes

Primary

Measure	Time frame
The amount of wrinkles. Timepoint: Before treatment and six month after the last session. Method of measurement: Visio face.	—

Secondary

Measure	Time frame
Inflammation. Timepoint: After each session. Method of measurement: Questionnaire and visit.;Intensity of pain. Timepoint: Treatment time. Method of measurement: Questionnaire and visit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and Stem cell Research Center of Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026