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PRP Versus Tranexamic Acid mesoneedling in Melasma Treatment

Platelet Rich Plasma Versus Tranexamic Acid mesoneedling in Melasma Treatment: A Split Face Comparative Study

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N12
Enrollment
45
Registered
2022-05-01
Start date
2022-04-19
Completion date
Unknown
Last updated
2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma. Other disorders of pigmentation

Interventions

Intervention 1: Intervention group: At each session, the right side of the patient's face receives PRP along with microneedling. Intervention 2: Control group: At each session, the left side of the pa

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: People with melasma on the cheeks and other areas of the face

Exclusion criteria

Exclusion criteria: Any complication that is related to the treatment process or is not tolerated by the patient The patient does not want to continue treatment for any reason Cancers, pregnancy, lactation, DVT, pulmonary embolism, stroke Incidence of drug allergies Occurrence of hypertrophic or colloidal scars at the treatment site

Design outcomes

Primary

MeasureTime frame
Melasma area recovery rate. Timepoint: Before treatment and 1 month after the last session. Method of measurement: Visioface.

Secondary

MeasureTime frame
Side effects. Timepoint: One week after session. Method of measurement: Questionnaire and visit.;Satisfaction. Timepoint: 1 months after the last session. Method of measurement: Questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and stem Cell Research Center, Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026