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Evaluation of the efficacy of conditioned medium derived from human umbilical cord Wharton jelly mesenchymal stem cells in the treatment of alopecia areata

Evaluation of the efficacy of conditioned medium derived from human umbilical cord Wharton jelly mesenchymal stem cells in comparison with intralesional triamcinolone in the treatment of alopecia areata

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200127046282N10
Enrollment
28
Registered
2022-03-30
Start date
2022-04-19
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alopecia areata. Alopecia areata, unspecified

Interventions

Intervention 1: Intervention group: Patients receive medium conditioning for 6 sessions 2 weeks apart by injection. Intervention 2: Control group: Patients receive triamcinolone injection for three se

Sponsors

Skin and Stem Cell Research Center, Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Men and women with alopecia areata Age 18 years and older and less than 50 years Complete patient consent to participate in the project

Exclusion criteria

Exclusion criteria: Platelet disorders Thrombocytopenia Patients receiving anticoagulants Patients with malignancy Receiving chemotherapy during the last 5 years Patients with sepsis Being a smoker Pregnancy Active wound or infection at the treatment site Do not receive any topical or systemic medication in the last 3 months Women with hyperprolactinemia Women with hormonal disorders or polycystic ovaries

Design outcomes

Primary

MeasureTime frame
The amount of hair loss. Timepoint: Before treatment and three month after the last session. Method of measurement: Trichoscan.

Secondary

MeasureTime frame
Side effects. Timepoint: One week after session. Method of measurement: Standard for pharmacovigilance research group in europe questionnaire and visit.;Satisfaction. Timepoint: Three months after the last session. Method of measurement: Patient consent questionnaire and visit.;Tolerability. Timepoint: Each session after transplantation. Method of measurement: Patient tolerance questionnaire and visit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSona Zare

Skin and stem Cell Research Center, Tehran University of Medical Sciences

sonazarebio@gmail.com+98 21 2665 7438

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026