Multiple sclerosis(MS). Multiple sclerosis
Conditions
Interventions
Intervention 1: Intervention group: Task-oriented training + anodal tDCS cerebellum and DLPFC. Intervention 2: Intervention group: Task-oriented training + anodal tDCS cerebellum. Intervention 3: Inte
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 55 Years
Inclusion criteria
Inclusion criteria: Age between 20-55 years old Presence of relapsing-remitting MS The average level of disability is between 2 and 5 in EDSS Having at least third middle school education in order to fill out the questionnaires Receiving stable drug treatments in the last 6 months Having a balance disorder based on the timed up and go test Absence of fixed contract not suffering from other neurological disorders Absence of obvious postural disorders in the spine No history of lower limb surgery Absence of cardiovascular diseases and diabetes Absence of any intracranial metal implants or other implanted devices such as pacemakers, cochlear implants Inability to stand or walk with or without the use of an assistive device
Exclusion criteria
Exclusion criteria: Multiple sclerosis attack within the last month Not being in the stable phase of MS pregnancy Dissatisfaction with treatment Inability to stand or walk with or without the use of an assistive device
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Balance score in Timed up and go test. Timepoint: Balance measurement at the beginning of the study (before the start of the intervention) and after 4 weeks and one month after the last treatment session. Method of measurement: Timed up and go test (TUG). | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigating static balance along with cognitive work through pressure point fluctuations on the force plate. Timepoint: Measuring static balance along with cognitive work at the beginning of the study (before the start of the intervention) and 4 weeks after the treatment and one month after the last treatment session. Method of measurement: Force plate.;Investigating spasticity by modified Ashworth questionnaire. Timepoint: Assessment of spasticity at the beginning of the study (before the start of the intervention), 4 weeks after the treatment and one month after the last treatment session. Method of measurement: Modified Ashworth scale.;Assessment of gait by 12-item gait scale in multiple sclerosis (12-MSWS). Timepoint: Assessment of walking at the beginning of the study (before the start of the intervention), 4 weeks after the treatment and one month after the last treatment session. Method of measurement: 12-item walking scale in people with multiple sclerosis(12-MSWS).;Assessment of neuromodulation by somatosensory evoked potentials. Timepoint: Evaluation of neuromodulation at the beginning of the study (before the start of the intervention), 4 weeks after the treatment and one month after the last treatment session. Method of measurement: Somatosensory evoked potential apparatus.;Examining the level of fatigue using the modified MS fatigue questionnaire(MFIS). Timepoint: Evaluation of fatigue at the beginning of the study (before the intervention), 4 weeks after the treatment and one month after the last treatment session. Method of measurement: Modified fatigue impact scale(MFIS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMinoo khalkhali Zavieh
Shahid Beheshti University of Medical Sciences
Outcome results
None listed