The Effect of Lawsonia Inermis Leaves extract on Wound Healing

Comparison of the Effectiveness of Lawsonia Inermis Leaves Extract Ointment with Phenytoin Ointment on Post Operative Pilonidal Sinus Wound

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200125046248N1

Enrollment

Registered

2022-05-26

Start date

2021-12-22

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound

Interventions

Intervention 1: Intervention group: One percent ointment containing aqueous extract of Lawsonia Inermise leaves at the base of Eucerin, which is coated topically twice a day for one month whole wound

Eligibility

Sex/Gender

All

Age

10 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age 10 to 70 years BMI < 35

Exclusion criteria

Exclusion criteria: History of allergy to the compounds in Lawsonia Inermis Underlying diabetes, cancer, and immune deficiency History of radiotherapy and chemotherapy

Design outcomes

Primary

Measure	Time frame
Wound volume. Timepoint: 7, 14 and 28 days after starting topical ointment. Method of measurement: Complete wound filling with normal saline to measure wound volume with Syringe.;Wound healing time. Timepoint: 7, 14 and 28 days after starting topical ointment. Method of measurement: Wound examination to determine the time of complete wound healing.;Wound erythema. Timepoint: Wound examination for wound erythema 7, 14 and 28 days after starting topical ointment. Method of measurement: Visual examination.;Discharge from wound. Timepoint: Wound examination to evaluate any discharge 7, 14 and 28 days after starting topical ointment. Method of measurement: Visual examination.;Wound length. Timepoint: Wound length measurement 7, 14 and 28 days after starting topical ointment. Method of measurement: Caliper device.;Wound Depth. Timepoint: Wound depth measurement 7, 14 and 28 days after starting topical ointment. Method of measurement: Caliper device.	—

Measure

Time frame

Wound volume. Timepoint: 7, 14 and 28 days after starting topical ointment. Method of measurement: Complete wound filling with normal saline to measure wound volume with Syringe.;Wound healing time. Timepoint: 7, 14 and 28 days after starting topical ointment. Method of measurement: Wound examination to determine the time of complete wound healing.;Wound erythema. Timepoint: Wound examination for wound erythema 7, 14 and 28 days after starting topical ointment. Method of measurement: Visual examination.;Discharge from wound. Timepoint: Wound examination to evaluate any discharge 7, 14 and 28 days after starting topical ointment. Method of measurement: Visual examination.;Wound length. Timepoint: Wound length measurement 7, 14 and 28 days after starting topical ointment. Method of measurement: Caliper device.;Wound Depth. Timepoint: Wound depth measurement 7, 14 and 28 days after starting topical ointment. Method of measurement: Caliper device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Arsalan Khosravi

Shahed University

a.khosravi@shahed.ac.ir009851214055

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026