Comparison of the effect of tranexamic acid and intravenous desmopressin on reducing bleeding during septorhinoplasty.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200124046241N1

Enrollment

175

Registered

2020-03-01

Start date

2019-03-21

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Septorhinoplasty. Rhinocerebral mucormycosis

Interventions

Intervention 1: Intervention group: Intravenous tranexamic acid, produced by Caspian Drug Co., 500 mg / 5 ml, half an hour before surgery, 5 mg / kg, intravenously. Intervention 2: Intervention group:

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Perform septorhinoplasty No coagulation disorders 18 Years until 50 Years ASA-1

Exclusion criteria

Exclusion criteria: Contraindications for the administration of Tranexamic acid and Desmopressin Dissatisfaction with research Drug addiction Being a smoker

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: During surgery. Method of measurement: The amount of bleeding is determined by the volume of the suction and the number of blood gases.	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: During surgery. Method of measurement: With barometer.;Heart rate. Timepoint: During surgery. Method of measurement: Pulse Oximeter.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTaimaz Amiraslani

Iran University of Medical Sciences

Golezard1@gmail.com+98 21 2278 5427

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026