The comparison of efficacy and outcomes of Triptorelin (Diphereline®) and hCG in ovulation trigger in infertile women with poly cystic ovarian syndrome

The comparison of efficacy and outcomes of Triptorelin (Diphereline®) and hCG in ovulation trigger in infertile women with poly cystic ovarian syndrome in IUI cycle: A randomize clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200122046221N3

Enrollment

120

Registered

2022-03-16

Start date

2022-02-20

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility in women with Poly cystic ovarian syndrome. Polycystic ovarian syndrome

Interventions

Intervention 1: Intervention group: Give two Letrozole tablets (2.5 mg) from Abureyhan Pharmaceutical Company, daily for 5 days for 3-7 days during only one menstrual cycle and then trans vaginal ult

Eligibility

Sex/Gender

Female

Age

15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Infertile women who do not become pregnant one year after cohabitation and intercourse without the use of contraceptives From 15 years old to 45 years old With Poly cystic ovarian syndrome

Exclusion criteria

Exclusion criteria: Semen analysis and abnormal hysterosalpingography Over 45 years old Myoma Hyperprolactinemia Hypothyroidism Hyperthyroidism FSH> 12 Women with endometriosis History of contact with any substance induced by previous ovulation Kidney and liver disease Any contraindications to Diphereline and hCG Male factor

Design outcomes

Primary

Measure	Time frame
Pregnancy. Timepoint: End of menstrual cycle. Method of measurement: Serum b-hCG.	—

Secondary

Measure	Time frame
Incidence of ovarian hyperstimulation syndrome. Timepoint: End of menstrual cycle. Method of measurement: Clinical signs and ultrasound.;Incidence of multiple birth. Timepoint: End of menstrual cycle. Method of measurement: ultrasound sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAthar Rasekhjahromi

Jahrom University of Medical Sciences

A.rasekh@jums.ac.ir+98 71 5433 1521

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026