Evaluation of varicocele surgery on deoxyribonucleic acid fragmentation index

Evaluation of the effect of new method of varicocele surgery (gobernectomy and) on fertility based on DNA fragmentation index

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200122046220N2

Enrollment

Registered

2021-04-04

Start date

2020-09-22

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility associated with varicocele and impaired DFI.

Interventions

Intervention 1: Control group: People over the age of 18 with varicocele and infertility who have impaired Deoxyribonucleic acid Fragmentation Index in semen analysis (DFI > 30%) undergoing varicocel

Eligibility

Sex/Gender

Male

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Infertile people with second and third degree varicocele Impaired Deoxyribonucleic acid fragmentation index

Exclusion criteria

Exclusion criteria: History of orchitis or testicular cancer Azoospermia History of inguinal or scrotal surgery Systemic inflammatory disease History of testicular trauma,

Design outcomes

Primary

Measure	Time frame
Percentage of fertility and DFI improvement after surgery. Timepoint: DFI measurement before and three months after surgery. Method of measurement: Percentage of sperm with defective chromosomes to total sperms.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactArash Karimi Baba Ahmadi

Artesh University of Medical Sciences

arashkarimi86@yahoo.com+98 21 6693 8257

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026