The effect of exercise and vitamin D in postmenopausal women with metabolic syndrome

The interaction effect of aerobic exercise and vitamin D supplementation on serum levels of apelin, vaspin and inflammatory factors in postmenopausal women with metabolic syndrome

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20200122046217N1

Enrollment

Registered

2020-08-14

Start date

2020-07-10

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic syndrome disease. Metabolic syndrome

Interventions

Intervention 1: Intervention group: The aerobic training + vitamin D supplementation Intervention will be consists of 20-40 minutes of aerobic exercise at 60% - 75% of HRmax, 3 times a week for eight

Eligibility

Sex/Gender

Female

Age

50 Years to 60 Years

Inclusion criteria

Inclusion criteria: confirmation of metabolic syndrome based on ATPIII criteria Not having a specific diet and regular exercise program in the past year 25-OHD serum levels between 10 and 20 ng/ml Being in menopause age

Exclusion criteria

Exclusion criteria: Presence of other cardiovascular disease Surgical treatment of obesity Presence of any other chronic disease or skeletal disorders severe weight loss

Design outcomes

Primary

Measure	Time frame
Vitamin D levels. Timepoint: Prior to the beginning and at the end of the study. Method of measurement: By blood sampling.;Anthropometric indices. Timepoint: Before the study starts and after the study ends. Method of measurement: Using INBODY test.;Lipid profile. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Vaspin. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Apelin. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Interleukin-6. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Interleukin beta-1. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;C- reactive protein. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Tumor necrosis factor alpha. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.	—

Measure

Time frame

Vitamin D levels. Timepoint: Prior to the beginning and at the end of the study. Method of measurement: By blood sampling.;Anthropometric indices. Timepoint: Before the study starts and after the study ends. Method of measurement: Using INBODY test.;Lipid profile. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Vaspin. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Apelin. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Interleukin-6. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Interleukin beta-1. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;C- reactive protein. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.;Tumor necrosis factor alpha. Timepoint: Before the study starts and after it ended. Method of measurement: Blood sampling.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRastegar Hoseini

Razi University

R.hoseini@razi.ac.ir+98 83 3427 7605

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026