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Compare the effect of TIVA and isoflurane on the activity of liver enzymes in patients undergoing laparoscopic cholecystectomy

Compare the effect of TIVA and isoflurane on the activity of liver enzymes in patients undergoing laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200122046216N1
Enrollment
30
Registered
2020-02-10
Start date
2019-07-20
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic Cholecystectomy Surgery. Cholecystitis

Interventions

Intervention 1: After the patient enters the operating room, the supine position extends over the operating room bed and is monitored initially. An oximeter probe and pressure gauge cuff are attached

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Has no history of anesthesia in the past 6 months The patient's age is between 18 and 70 years old According to the ASA class, there will be one or two classes of anesthesia

Exclusion criteria

Exclusion criteria: The patient needs more medication during surgery Bleeding during surgery Laparoscopic change to laparotomy

Design outcomes

Primary

MeasureTime frame
Anesthesia by Tiva. Timepoint: Time to start anesthesia. Method of measurement: Mg / kg body weight.;Isoflurane Anesthesia. Timepoint: Anesthesia maintenance time. Method of measurement: Mac Anesthetic Evaporator.;ALT Liver Enzyme. Timepoint: Hepatic enzyme activity preoperatively and postoperatively and 24 and 48 hours postoperatively. Method of measurement: Biochemical Autoanalysis Device.;AST Liver Enzyme. Timepoint: Hepatic enzyme activity preoperatively and postoperatively and 24 and 48 hours postoperatively. Method of measurement: Biochemical Autoanalysis Device.;ALP Liver Enzyme. Timepoint: Hepatic enzyme activity preoperatively and postoperatively and 24 and 48 hours postoperatively. Method of measurement: Biochemical Autoanalysis Device.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdieh Dartomi

Bojnourd University of Medical Sciences

dartoomi1369m@gmail.com+98 58 3229 7095

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026