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Laser in lichen planus

Evaluating the efficacy of the Er-Cr-YSGG laser before topical corticosteroid therapy in treatment of Oral lichen planus

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20200119046187N1
Enrollment
40
Registered
2020-04-11
Start date
2019-11-09
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral lichen planus. Lichen planus

Interventions

Intervention 1: Intervention group:Before starting drug treatment, this group is under laser radiation (Er.Cr.YSGG) with the specifications of the American Waterlase device (with 2780 nm parameters, e

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Lichen planus Patients with symmetrical two focal parts Patient satisfaction and cooperation

Exclusion criteria

Exclusion criteria: Recurrence history Mucocutaneous involvement Take effective medications over the past month The history of the cancer in the head and neck History of proliferative diseases History of thyroid disease Pregnancy Keratotic lichen planus

Design outcomes

Primary

MeasureTime frame
Oral lichen planus lesions recovery time:time to reach score 1 or zero according to Thongprasom sign scoring in weeks 1 to 8. According to Thongprasom sign scoring in oral lichen planus lesion the score is from zero to five. Zero score: no wounds - Natural mucus, score 1: mild white steria , score 2: white steria with atrophic and erythematous areas (less than 1 cm square), score 3: white steria with atrophic and erythematous areas (more than 1 cm square), score 4: White steria with ulcerative (less than 1 cm square), score 5: White steria with ulcerative (more than 1 cm square). Timepoint: In each session before treatment, 8 times in 8 consecutive weeks. Method of measurement: By collis and clinical observation.;The severity of the lesion is based on Thongprasom sign scoring (categories 0 to 5). Timepoint: In each session before treatment, 8 times in 8 consecutive weeks. Method of measurement: By the collis and clinical observation in each session before the start of treatment in mm / cm (categories 0 to 5).

Secondary

MeasureTime frame
Burning intensity: Verbal Analog scale (score 0 to 10):The patient's severity of discomfort from the burning for each lesion is measured separately by the analog scale verbal criteria, so that the number zero is considered as non-irritating and the number ten is considered as the highest possible burn and the patient is asked to number In this interval, select as the intensity of the burn. Timepoint: In each session before treatment, 8 times in 8 consecutive weeks. Method of measurement: By determining the number by patients in each session before starting treatment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamidreza khalighi

Shahid Beheshti University of Medical Sciences

dr.hkh92@gmail.com+98 21 2990 2302

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026